Off-site cloud backup (eg Amazon S3, Wasabi)

I’d like to synchronise our mail store to an Amazon S3 bucket or similar, for protection from ransomware.

Server is running on macOS with maildir.

Should I use a Dovecot process, rsync, a Mac app like Arq or Jungle Disk, or something else?

Anyone have experience or opinions on this?

Thanks,

James.